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Change in PVR at Week 16
(OPSYNVI® vs macitentan)1
Change in PVR at Week 16
(OPSYNVI® vs tadalafil)1
Treatment with OPSYNVI® (macitentan/tadalafil) resulted in a statistically significant treatment effect in PVR vs macitentan monotherapy and tadalafil monotherapy1
CL=confidence limits; PAH=pulmonary arterial hypertension; PVR=pulmonary vascular resistance.
Reference: 1. OPSYNVI® (macitentan/tadalafil) full Prescribing Information. Actelion Pharmaceuticals US, Inc.